Liraglutide - A Good Drug For Treating Diabetes Mellitus Type 2 And Obesity

1. Liraglutide 

Liraglutide (204656-20-2) is medication sold under different brand names in various parts of the world, which are used for different therapeutic purposes. The most common Liraglutide brand names on the market today are Victoza and Saxenda. The Liraglutide uses depend on the brand that you purchase, for instance, Victoza is mostly used with proper exercise and diet to boost blood sugar control in adults and type 2 diabetes mellitus in children of at least ten years old. In addition, Victoza has also proved to be vital in reducing risks of heart problems such as stroke or heart attack in adults with heart diseases and type 2 diabetes.

On the other hand, Saxenda, which also another Liraglutide brand, is used with proper diet and exercise to help users to lose weight when suffering from various health conditions. Despite being a Liraglutide brand name, Saxenda is not used for the treatment of type 1 or type two diabetes, and it’s also not an appetite suppressant or weight-loss supplement. Your doctor can also recommend Liraglutide uses for other reasons not included in this guide. However, it’s advisable to always get the right Liraglutide dose from your doctor for better results.

Liraglutide for sale is available on various online stores and physical pharmacies, but you should always be careful about your source. Always do proper research to ensure that you get your drug from a reliable and experienced seller.  Quality of the medication that you take has an impact on the results you will experience at the end of the dosage cycle. The Liraglutide cost can vary from one source to another but make sure you get the best quality. If you are not sure about the source, consult with your medic.

2. Liraglutide structure 

Chemically, Liraglutide structure is made up of a long-acting fatty acylated glucagon-like peptide that is administered subcutaneously together with antihyperglycemic activity. The drug’s prolonged action is a result of fatty acid, and palmitic acid attachment to GLP-1, which binds easily with albumin. The albumin binding plays a vital role in protecting Liraglutide from immediate degradation once you take your dosages, and as a result, it leads to a consistent and slow release of GLP-1. This ensures that you get the desired results within the shortest time possible.

3. Liraglutide indication 

FDA has approved both Victoza and Saxenda for the treatment of different medical conditions in the United States of America. As mentioned earlier, Victoza has been approved for the treatment of heart problems and type 2 diabetes. It’s also known for reducing gastrointestinal symptoms such as vomiting, nausea, and diarrhea. The Saxenda was also approved by the FDA to help in the treatment of obesity and body weight control. Liraglutide should be taken when you want to reduce cardiovascular problems which result from heart diseases or type 2 diabetes mellitus. Also, if you want to control your body weight resulting from type 2 diabetes mellitus, Liraglutide obesity will be an excellent drug for you.  Liraglutide obesity has also helped many users to manage their weight. Even if you experience the symptoms that can be treated with Liraglutide powder, don’t take the drug without consulting with a health professional. However, remember that your doctor can also prescribe this drug for you to help in the treatment of any other medical condition not listed in this article.

4. Liraglutide mechanism of action 

In many cases, Liraglutide works depending on what you want to achieve by the end of the dosage cycle. For instance, the Liraglutide mechanism of action for people taking liraglutide dose for weight loss is different from users who are taking it for the treatment of type 2 diabetes mellitus. The two Liraglutide brands names Victoza and Saxenda work differently once they get into your body system.

For instance, Liraglutide obesity (Saxenda) works by suppressing the production of appetite hormones (glucagon-like-peptide or GLP-1) in your body, which regulates your hunger.  The moment the GLP-1 production goes down, your appetite will go down and end up eating fewer calories, and in the long run, lose your body weight. Calories are responsible for your increased body weight, and if you can control them, then it will be easy for you to shed some pounds.

On the other hand, Victoza works in three different ways to deliver the results promised by the drug manufacturer. First, Victoza works by slowing down the food leaving your stomach, which regulates the blood sugar levels in your body. Though the same mechanism, the medication also prevents your liver from producing too much sugar. Lastly, Liraglutide, which is the major component in the Victoza, also stimulates your pancreas to produce more insulin when blood sugar levels are high. The drug enhances all these activities by boosting the beta cells’ effectiveness. The cells help in controlling blood sugar by releasing insulin, which neutralizes the sugar levels in your body system.  The stimulation of insulin production in your body is the primary reason why Victoza is mainly used in the treatment of type 2 diabetes mellitus.

5. The Dosage and Administration Instructions of Liraglutide 

Liraglutide uses vary from one user to another depending on the health condition being treated. The drug’s dosage should be set by a medical professional depending on the condition being treated. Children under the age of ten are not advised to take this drug, as it can expose them to severe side effects. The human bodies are also different, and that’s why it’s always advisable to go for medical examination before you start taking any drug. Although Liraglutide comes with dosage instructions suggested by the manufacturer, sometimes it might not work for you. The doctor is the only right person to set the right Liraglutide dosage for you after examining your health condition.

• Liraglutide injection

Liraglutide is an injectable drug that should be administered in your upper arm, abdomen, or thigh. There is no specific set time for you to take your Liraglutide dose, but you can take it with or without meals.  You can always rotate the liraglutide injection sites to reduce the side effects or the pains that you might experience in the area. The dose administration time can be changed comfortably without adjusting the set dosage. It’s advisable always to inspect every Liraglutide injection visually; you should only take your injection when the solution is colorless, clear, and doesn’t have any visible particles. In case your solution develops any unusual color, don’t take it without consulting with your doctor.

• Liraglutide dose

Liraglutide powder dosage will depend on your body tolerance, age and the health condition being treated.

Adult dosage

•  Diabetes type 2

The initial Liraglutide powder (204656-20-2) dose for adults is 0.6mg, which should be taken once per day for one week. After the one week, the dosage can be adjusted to 1.2mg subcutaneously once per day, and if you don’t achieve the control over the disease, your doctor can increase the dosage further to 1.8mg per day. The Liraglutide maintenance dose should be between 1.2 and 1.8 mg per day. However, the maximum dose is 1.8mg per day.

The 0.6mg initial dose per day is intended to minimize the gastrointestinal symptoms resulting from the therapy initiation and cannot be sufficient enough for glycemic control.  However, Liraglutide is not insulin substitutes and patients with type 1 diabetes mellitus or diabetic ketoacidosis should not take it.  When you start this therapy, consider reducing the insulin secretagogue to minimize the hypoglycemia risk.

• Cardiovascular risk reduction

The initial Liraglutide dosage for adults with cardiovascular problems is 0.6mg per day and should be taken for the first week. The dosage should be increased to 1.2mg per day in the following week, and if you don’t achieve the glycemic control, your doctor should increase the dosage further to 1.8mg per day. However, by the time the Liraglutide powder dose is increased to the maximum, you will have attained the desired results. The maintenance dosage should be between 1.2mg and 1.8mg per day, while the maximum adult dose is 1.8mg per day.

• Liraglutide adult dose for weight loss or obesity

The liraglutide weight loss dosage increase should be adhered to, to minimize the possibility of experiencing gastrointestinal symptoms. The dosage adjustment can be delayed for an additional week for better results. However, your doctor should guide you in this process. The initial dosage here is 0.6, which should be taken subcutaneously once per day. In the second week, the dose could be increased to 1.2mg per day; in the third week, the dosage can be raised further to 1.8 per day. In the fourth week, the dosage should also be increased to 2.4mg and the fifth week to 3mg once per day. However, your doctor will guide you on when and how to improve the dosage.

The maintenance dose here is 3mg once per day, but in case your body cannot tolerate it, the doctor can advise you to discontinue the dosage. Chronic weight management using this drug has only been attained with high dosages. On obesity, the Saxenda Liraglutide brand has proved to be vital in weight management, and the drug is not used for the treatment of type 2 diabetes mellitus.  However, Victoza is known for the treatment of type 2 diabetes mellitus and cardiovascular problems.

• Pediatric Dosage

Liraglutide injection dosage should only be taken by children of at least ten years old and above. Any kid lower than that should not be given this drug even if they show symptoms that could be treated with this peptide. The pediatric liraglutide dosage also depends on the health condition being treated. The recommended dosages are as follows;

Pediatric dosage for Diabetes type 2

The recommended initial Liraglutide injection dosage is 0.6mg, which should be taken once per day for at least one week. After that, the dose can be increased to 1.2mg per day, and if glycemic control is not attained, the medic can increase the dose further to 1.8 gm in the following week. The maximum pediatric dose for diabetes type two is 1.8mg per day, while the maintenance dose ranges from 0.6mg to 1.8mg per day.

The liraglutide can also be prescribed to children to help in the treatment of different health conditions such as renal and liver problems. However, when treating these two conditions, you should take Liglutide carefully as it can lead to severe side effects when overdosed. No dose adjustment is recommended when taking liraglutide peptide for liver or renal issues. When taking liraglutide dosage, reduce any insulin intake to minimize the risk of hypoglycemia.

• What happens if I overdose?

Overdosing any drug is not a good idea and shouldn’t be encouraged even when taking a Liraglutide dose for weight loss or treatment of any other health condition. You are advised to always stick to the dosage instructions given by your doctor. Overdosing will lead to severe side effects, which might worsen your health condition or even lead to other health complications. However, sometimes, overdosing can be a result of an accident or your body’s reaction to the drug. The most common overdosing side effects include severe nausea and vomiting. When you notice you have taken more dosage than recommended, seek medical attention as soon as you can. You can also reach out to your doctor for assistance.

6. What are the benefits of Liraglutide? 

Over the years, Liraglutide has proved to deliver different benefits, especially in the medical world. However, you can only experience maximum liraglutide benefits, if you stick to the dosage instructions and proper diet or exercise as advised by your doctor. Here are some of the most known Liraglutide benefits.

Enhances Type 2 diabetes

Liraglutide brand name Victoza has been used and approved by the FDA for the treatment of diabetes type 2. The drug helps in controlling blood sugar in your body. When the sugar levels are high in your body, liraglutide stimulates your pancreas to produce more insulin enzyme which helps in neutralizing the blood glucose.

Help in fighting Obesity and body weight

In the United States of America, FDA approved Liraglutide for treatment of obesity after it proved to be effective in suppressing appetite and intake of calories which helped in body weight management. On average, women have experienced significant weight loss when they take liraglutide weight loss than men. However, that doesn’t mean that men will not benefit from this drug. For better weight loss experience with this drug, proper diet and exercise should also be accompanied with the dosage.

Protects the Vascular system

The liraglutide has proved to be essential in protecting your heart muscles and lower the risk of heart diseases. Medical studies also show that taking liraglutide, improved heart diseases that result from type 2 diabetes mellitus and obesity. The drug also helps in balancing your blood pressure, which aids in boosting your vascular health.
This drug is also said to have a positive impact on improving your brain health, help in control of anxiety, and it can serve as an anti-oxidant and anti-inflammatory supplement. In another medical study, liraglutide showed that it could help people with alcohol addiction. However liraglutide overdose can expose you to health complications and ruin all the expected benefits.

7. You should take care of the following side effects/warning when use Liraglutide 

Almost every drug, when misused or overdosed can expose you to severe side effects, and liraglutide is not exceptional. However, sometimes the side effects can be as a result of how your body responds to the liraglutide weight loss dose. Some liraglutide warnings are usual and disappear with time, but in case the following effects don’t disappear with time or they become too severe, seek medical attention;

• Runny nose, cough or sneezing
• Severe headaches
• Burning or difficulty in urinating
• Liraglutide Injection sites rednessor rashes
• Constipation and heartburn

There are very severe liraglutide warnings which require immediate medical attention once you start experiencing them, and they include;

• Clay-colored stools
• Yellow skin or eyes
• If you start thinking about killing, harming yourself or others
• Diarrhea
• Nausea, swelling throat, tongue, face, eyes or mouth.
• Difficultly in swallowing or breathing.

For these serious Liraglutide side effects, you are advised to stop taking the dosages immediately as you look for medical assistance.

8. Liraglutide interactions 

The drug interactions can affect how your medication will work or even put you on a high risk of experiencing severe side effects. Therefore, before you start taking Liraglutide dose, it’s essential to inform your doctor about any other health condition you are under medication. Some drugs can’t work together, and it’s good for your doctor to be in the know about any other medicine you might be taking. To be on the safe side, don’t start, change the dosage or stop taking any medication without consulting with a medical professional.

You are advised not to take any this drug with any other medication containing Liraglutide as it can lead to overdosing and expose you to severe side effects. Depending on your health condition, your doctor will provide you with the right Liraglutide interactions to enhance the results. There are many drugs that you can take together with Liraglutide such as acetohexamide, albuterol, cinoxacin and danazol, among many others.

9. Clinical Experience 

According to liraglutide reviews on different online platforms, many users are satisfied with the results and benefits they have enjoyed while or after taking the drug. Medical studies also show how the drug has been useful in the treatment of various medical conditions such as obesity, type 2 diabetes mellitus, renal problems and in preventing heart diseases resulting from different health conditions. The liraglutide interactions have also proven to be potent in treating diabetes type 2 in children of at least ten years old.

However, some users have had a bad experience with this drug, but that can be attributed to Liraglutide overdose or body tolerance. The good news is that the liraglutide side effects can be reversed if you contact your doctor in good time. The best way to avoid experiencing severe side effect while taking this drug is going for medical examination before you start your dosage and allowing the medics to set the right dosage for you. It’s also advisable to follow dosage instructions and inform your doctor about any other drug you might be taking.

10. Conclusion  

This drug has proven to be essential in the medical world more so in the treatment of obesity, type 2 diabetes and heart problems, among others. Liraglutide powder (204656-20-2) for sale is available on different online stores, but you will find it in various brand names such as Saxenda and Victoza. However, make sure you understand what each brand is used for before making your order. As mentioned above, each liraglutide brand name is used for a specific purpose. Saxenda is approved for weight loss and treatment of obesity while Victoza is used in type 2 diabetes treatment as well as heart diseases resulting from high blood sugar levels.  However, follow the dosage instructions to avoid experiencing the Liraglutide side effects.

It’s advisable to do proper research about your liraglutide buy source before making your purchases. Today there are many peptide sellers on the market, making it hard for you to know where to get a quality drug that will guarantee you impressive results. Look at the liraglutide reviews on the vendor’s website to get an overview of the products and how the seller operates. Choosing the most experienced and reputable liraglutide buy supplier will assure you of quality services as well as quality medical products. Liraglutide cost varies from one vendor to another.

You don’t have to worry about anything when taking Liraglutide since it’s a legal drug and for better results, involve your medic in the entire dosage cycle.

References

1. Kaakeh, Y., Kanjee, S., Boone, K., & Sutton, J. (2012). Liraglutide‐induced acute kidney injury. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 32(1), e7-e11.
2. Marso, S. P., Daniels, G. H., Brown-Frandsen, K., Kristensen, P., Mann, J. F., Nauck, M. A., … & Steinberg, W. M. (2016). Liraglutide and cardiovascular outcomes in type 2 diabetes. New England Journal of Medicine, 375(4), 311-322.
3. Lind, M., Hirsch, I. B., Tuomilehto, J., Dahlqvist, S., Ahrén, B., Torffvit, O., … & Sjöberg, S. (2015). Liraglutide in people treated for type 2 diabetes with multiple daily insulin injections: randomised clinical trial (MDI Liraglutide trial). Bmj, 351, h5364.
4. Davies, M. J., Bergenstal, R., Bode, B., Kushner, R. F., Lewin, A., Skjøth, T. V., … & DeFronzo, R. A. (2015). Efficacy of liraglutide for weight loss among patients with type 2 diabetes: the SCALE diabetes randomized clinical trial. Jama, 314(7), 687-699.